LIQUEN AMILOIDE PDF

The pale amorphous material in the papillary dermis appears globular, suggestive of amyloid. This had become noticeably darker over the past several years. Scanning magnification of an auricular papule as shown in Fig. In both patients punch biopsies from the conchal bowl yielded a pauci-inflammatory specimen with orthohyperkeratosis and acanthosis Fig. Subscriber If you already have amilolde login data, please click here. The most prominent difference between the two forms is that clinically and histologically lichen amyloidosis shows features of chronic rubbing.

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Gajora Macular amyloidosis is more subtle in appearance, manifesting as brown macules or papules that coalesce into irregularly pigmented patches or plaques, which may or may not be pruritic, and develop most often on the interscapular back. In addition, one of the patients had macular amyloidosis of the upper back.

Follicular plugging is prominent. Histopathology of the rippled plaque depicted in Fig. These cases differ from lichen amyloidosis in that the lesions tend to be plaque-like or nodular and are derived from immunoglobulin light chains. There are several case reports of cutaneous amyloidosis of the auricle occurring in the setting of systemic amyloidosis [ ]. Subscriber If you already have your login data, please click here.

Liquen amiloide en las piernas Piel. Ami,oide all, at least a dozen cases of lichen amyloidosis of the auricular concha have been reported in the English literature with additional reports existing in French [ 8 ], Spanish [ ], and Portuguese [ 11 ].

Lichen amyloidosis and macular amyloidosis are likely the result of focal epidermal damage, although this has not been conclusively proven. Electron microscopy showed straight, non-branching intermediate filaments densely woven into bundles, which are highly typical for amyloid. Summary and related texts. Si continua navegando, consideramos que acepta su uso. Another similar report of biphasic amyloidosis by Barnadas [ 7 ] involving the auricular canal not only documented Congo Red positivity but also positive staining with anti-keratin antibodies.

Review of systems was unremarkable and negative for alopecia, arthralgia, oral sores, and photosensitivity. Rarely, it is reported to occur as an inherited familial condition [ 2 ]. Cutaneous manifestations of systemic amyloidosis are observed mainly in individuals with a plasma amiiloide dyscrasia, often multiple myeloma. It is thought to be more common in the Asian population. An electron micrograph of an auricular papule from patient 1. Lichen amyloidosis is a rare chronic form of cutaneous amyloidosis see this terma skin disease characterized by the accumulation of amyloid deposits in the dermis, clinically characterized by the development of pruritic, often pigmented, hyperkeratotic papules on trunk and extremities, especially on the shins, and histologically by the deposition of amyloid liqjen amyloid-like proteins in the papillary dermis.

Acanthosis and hyperkeratosis are evident, as well as a broad band of light staining amorphous material in the papillary dermis. The first patient is a year-old woman who presented with a 4-year history of pruritic lesions that started in the conchal bowl of her left ear, and soon after appeared on the right side as well.

In addition to these three forms, cutaneous amyloidosis can also be an incidental histopathologic finding in various neoplasms. Se continuar a navegar, consideramos que aceita o seu uso. In these instances, auricular papules were associated with more widespread cutaneous amyloid elsewhere.

Analogous to hyperkeratotic lichen planus seen on the shins, lichen amyloidosis can be thought of as hyperkeratotic primary cutaneous amyloidosis. The majority of cases of nodular amyloidosis are unassociated with underlying hematological malignancy [ 3 ].

Dermatology Online Journal SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. The second patient is a liqien woman amiloire presented with a long-standing pruritic rash on her upper back. Are you a health professional able to prescribe or dispense drugs? For all other comments, please send your remarks via contact us. The two major forms of primary localized cutaneous amyloidosis are lichen amyloidosis and macular amyloidosis.

Systemic amyloidosis involves the deposition of amyloid in multiple tissues. Other search option s Alphabetical list. The auricular concha is a recognized although unusual site for lichen amyloidosis, and here two additional cases are reported. Lichen amyloidosis occurs primarily on the shins, although other mainly acral sites may be involved.

No evidence of interface dermatitis was detected. These are the options to access the full texts of the publication Piel. Amyloid globules can usually be visualized by light microscopy but are enhanced by crystal violet, thioflavin S, or Congo red stains. Physical exam was remarkable for bilateral, symmetrical brown scaly mm monomorphous papules mainly on the conchal bowls Fig. The documents contained in this web site are presented for information purposes only.

Her past medical history was significant only for hypertension. Show more Show less. Amyloidosis is a depositional disorder with diverse etiologies. Most 10 Related.

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