Das Pickwick-Syndrom wird auch als Obesitas-Hypoventilationssyndrom oder als Adipositas-bedingtes Hypoventilationssyndrom bezeichnet. Auch die Lunge wird durch die umliegenden Gewebemassen eingeengt. Insbesondere in der Nacht kommt es zu einer sogenannten Stenoseatmung. Es wird vermutet, dass die chronische Hyperkapnie dem Schutz der Atempumpe dient. Das Atemzentrum reagiert jedoch auf die chronische Hyperkapnie immer weniger, sodass es zu einer Verschiebung des Sollwerts in der Atmungsregulation kommt. Die Atmung wird vermindert und der Sauerstoffgehalt im Blut sinkt.
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What is Pickwickian syndrome? Pickwickian syndrome, clinically known as obesity hypoventilation syndrome OHS , is a condition that affects the blood.
When you breathe in oxygen, the air sacs, or alveoli, in your lungs transfer the oxygen into your bloodstream through capillaries. Capillaries are tiny blood vessels that connect to your bloodstream. These vessels also transfer carbon dioxide from your bloodstream to the air sacs.
This carbon dioxide is then removed from your blood when you breathe out. These steps are known as gas exchange. Gas exchange is important for keeping a healthy balance of oxygen and carbon dioxide in your blood. Joe had many of the symptoms later described by clinicians when they discovered this condition, including obesity and sleep apnea not breathing for extended periods of time during sleep. The name OHS is now more commonly used by doctors to describe the symptoms associated with this condition.
Symptoms Many Pickwickian syndrome symptoms are connected to the lack of oxygen in your blood. During sleep, your breathing can become shallow and may even stop for minutes at a time or longer.
Common Pickwickian syndrome symptoms include: feeling out of breath having a lack of energy feeling sleepy or fatigued during the day swelling or a bluish color in your fingers, toes, or legs known as cyanosis morning headaches due to high levels of carbon dioxide in your blood symptoms of depression, such as feelings of sadness, loss of interest in activities you normally enjoy, and suicidal thoughts There are also more serious symptoms of Pickwickian syndrome.
Talk to your doctor as soon as possible if you experience: obstructive sleep apnea, which happens when you have periods of not breathing at all while you sleep high blood pressure cor pulmonale , a term for what happens when low blood oxygen causes the right side of your heart to experience too much tension Causes No specific, direct cause of Pickwickian syndrome is known by doctors or researchers.
The stress that a high body weight puts on your joints is well known to cause osteoarthritis. This happens when the cartilage and bone in your joints start to become damaged or break down completely.
Obesity can also cause your fat cells, or adipose tissue, to attack your joint tissue. This can cause long-term inflammation that can cause your joints to become damaged, which can lead to osteoarthritis. Complications of Pickwickian syndrome can include: pulmonary hypertension, or high blood pressure edema, or fluid buildup, in your legs secondary erythrocytosis, or an abnormal amount of red blood cells in your bloodstream See your doctor immediately if you experience any of these complications.
Many treatment plans exist to help you manage the symptoms of Pickwickian syndrome. Weight loss The first line of treatment is weight loss. If your doctor concludes that your obesity is causing Pickwickian syndrome, they will likely recommend that you lose weight to bring your BMI into the normal range.
Obesity is one of the main causes of Pickwickian syndrome. Losing excess weight can help take the stress off your body and get your breathing back to normal.
You should also incorporate movement and walking back into your life. Make conscious and informed choices about everything you eat. Because Pickwickian syndrome can lead to numerous serious health disorders and even death, weight loss is essential. This machine provides oxygen from a motor into a tube that connects to a mask that you wear over your nose and mouth. This machine allows a constant flow of oxygen into your lungs, even when you sleep.
This allows your lungs to give more oxygen to your blood and prevent hypoxemia. CPAP is well- researched and effective in reducing sleep apnea and improving quality of sleep. There are numerous health benefits of a night of deep, solid sleep. With Pickwickian syndrome you will be on this machine day and night. Ventilator machine Your doctor may also recommend using a ventilator to make sure that your breathing is consistent.
A ventilator machine moves oxygen in and out of your lungs and can help balance the oxygen and carbon dioxide in your lungs. In this procedure, your doctor cuts a hole open in your trachea, or windpipe, and inserts a tube to allow consistent breathing. Weight loss surgery options Your doctor may also recommend weight loss surgery, also known as bariatric surgery, to help you manage your weight.
Some common weight loss surgery options include gastric bypass and laparoscopic adjustable gastric banding. Both surgeries limit the amount of food that you can hold in your stomach.
You may need you to make some significant lifestyle changes if you choose either of these surgeries. Talk to your doctor about the benefits and costs of these surgeries before you decide to undergo any of them. Other possible treatments.
Síndrome de hipoventilación y obesidad (SHO)