Abstract Terminalia arjuna T. The lipid lowering activity of these four fractions A, B, C, and D was evaluatedin vivo in two models viz. Hyperlipidemia induced by triton caused marked increase in the plasma levels of total cholesterol Tc , triglyceride Tg and phospholipids PL in rats. After treament withT. After treatment withT.
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Akinogar The stem barks and leaves samples were dried by keeping them in open air under shade for three weeks till constant weight was achieved. The antioxidant capacities of arjuna extracts were also evaluated by measuring natioxidant free radical scavenging abilities to 1,1 —diphenyl-2 picrylhydrazyl DPPH stable following the previously established method [ 14 ] with slight modifications.
Antioxidant compounds terminate these chain reactions by removing free radical intermediates, and inhibit other oxidation reactions by being oxidized themselves [ 2 ]. The data regarding the percentage inhibition of peroxidation in linoleic acid system from arjuna extracts prepared in different solvent systems is presented in Figure 5. Free radical scavenging activity was evaluated using stable DPPH free radical antioxivant The remaining water in the plant material was removed using paper towel by pressing on them gently.
Extracts The data regarding the total flavonoid contents, 1. The earlier investigations in the relevant field had clearly demonstrated that methanol was a promising solvent for extraction of antioxidants from natural products [ 16 ].
The bark and leave samples of Terminalia arjuna L. Moreover, there is a growing awareness among consumers regarding food additive safety [ 5 ]. The absorbance of the resulting solutions and the blank were recorded after 1 hour at room temperature. A number of studies are available on the antioxidant activity and medicinal importance of this plant worldwide, whereas, in Pakistan no remarkable research work has been conducted while the plant is easily available due to favorable agro-climatic conditions for its growth.
Methanol is generally employed for the extraction of antioxidant components due to their zntioxidant and good solubility with many antioxidant components [ 17 ]. All the samples were analyzed in triplicates. Where, A blank is the absorbance of the control reaction mixture, and A sample is the absorbance of the sample.
The concentrated extract was allowed to dry at room temperature. A linoleic acid control was performed without the extracts. The oxidation reactions can produce free radicals, which start chain reactions and subsequently can cause a large number of cardiovascular diseases in humans [ 1 ]. Two different solvent systems aqueous ethanol water: The reducing power of a compound is related to its electron transfering ability and may serve as a significant indicator of its antioxidant activity [ 20 ].
The arjuna extracts being a good source of natural antioxidants should be further investigated to explore the chemistry of these extract. Reducing power of extract was determined according to the procedure described previously [ 15 ]. Extracts The synthetic antioxidants butylated hydroxyanisole, butylated hydroxytoluene, tertiary butyl hydroxyquinone and propyl atioxidant being used in food products to prevent oxidative damages in terms of food spoilage and rancidity in fatty foods [ 3 ] had been band in advanced countries and being discouraged even in developing countries due to their perceived carcinogenic attributes and other toxic properties [ 4 ].
After 3 minutes of shaking, the absorbance of mixtures was measured with spectrophotometer U, Hitachi Instruments Inc,Tokyo, Japan at nm taken as peroxide contents. Our findings regarding TPC of arjuna extracts were found in a close agreement with the findings 7. Qasim Ali, Assistant Professor of Botany. This suggests that extracts of Terminalia arjuna may be explored as a potential source of antioxidants for their use in food and pharmaceutical industries.
The methanol can be exploited for the extraction of effective antioxidant components from the plant material. The specimens was further identified and authenticated from Dr. Briefly, 50mg of dry mass of extracts was mixed with 0. J Food Process Technol 5: The active components of Terminalia arjuna are tannins, triterpenoid saponin arjunic acid, arjunolic acid, arjungenin, and arjunglycosides [ 11 ]. The upper layer of solution 5.
It can be concluded from the results of the present study that the antioxidant activity of Terminalia arjuna L extracts varied considerably depending on the nature of extracting solvents as well as the nature of raw materials to be extracted.
February 04, ; Accepted Date: Percent inhibition of linoleic acid peroxidation by synthetic antioxidant BHT was taken as control and compared with arjuna extracts. The plant is very rich source of natural antioxidants due to which it has been extensively investigated for its uses in both Ayurvedic and Yunani systems of medicine [ 78 ].
The different extracts from arjuna exhibited a close dependent reducing power and it was observed that reducing power of extracts from different extracts varied to some extent and found in the range of anntioxidant. The extraction yields of extracts were ranged from 6. February 28, Citation:.
ANTIOXIDANT ACTIVITY OF TERMINALIA ARJUNA PDF
This article has been cited by other articles in PMC. Abstract Terminalia arjuna, commonly known as arjuna, belongs to the family of Combretaceae. Its bark decoction is being used in the Indian subcontinent for anginal pain, hypertension, congestive heart failure, and dyslipidemia, based on the observations of ancient physicians for centuries. The utility of arjuna in various cardiovascular diseases needs to be studied further. Therefore, the present review is an effort to give a detailed survey of the literature summarizing the experimental and clinical studies pertinent to arjuna in cardiovascular disorders, which were particularly performed during the last decade. Systematic reviews, meta-analyses, and clinical studies of arjuna were retrieved through the use of PubMed, Google Scholar, and Cochrane databases. Most of the studies, both experimental and clinical, have suggested that the crude drug possesses anti-ischemic, antioxidant, hypolipidemic, and antiatherogenic activities.
Vudojar The plant is very rich source of natural antioxidants due to which it has been extensively investigated for its uses in both Ayurvedic and Yunani systems of medicine [ 78 ]. The antioxidants are molecules capable antioxidaant decreasing or preventing the oxidation of substrate molecules. In the present study, it was observed that methanol was an efficient solvent and stem bark extracts of arjuna were more rich in antioxidant compounds. The present results suggested that the methanolic extracts of arjuna are more active regarding the phenolic antioxidant compounds that could be exploited as potent source of natural antioxidants for functional food and pharmaceutics.